Aminophosphonic and Aminophosphinic Acids: Chemistry and Biological Activity
Editorial Reviews
Book Description
Aminophosphinic and aminoposphonic acids, synthetic analogs to natural amino acids, have attained a position of prominence in research--particularly in research involving the modification of physiological processes in living organisms.
Aminophosphonic and Aminophosphinic Acids provides a comprehensive insight into the chemistry and biological activity of these compounds. Separate chapters are devoted to naturally-occurring derivatives, synthetic procedures, structural, spectroscopic and analytical aspects, metal complexes, agrochemicals, neuroactive compounds and biomedical applications and transition-state analogue enzyme inhibitors, with particular emphasis on inhibitors of HIV protease, thrombin and human collagenase. This book is a valuable source of information for researchers working with these types of compounds in biomedical and agrochemical industries and all others working with synthetic analogues of biologically important molecules.
From the Back Cover
The key role of naturally-occurring amino acids in the chemistry of life and as structural units in peptides, proteins and enzymes has led to intense interest in the chemistry and biological activity of synthetic analogues. The phosphorus analogues of the amino acids have attracted a particular interest in the fields of research directed at the discovery, understanding and modification of physiological processes. Aminophosphonic and Aminophosphinic Acids provides a comprehensive insight into the chemistry and biological activity of these compounds. Separate chapters are devoted to naturally-occurring derivatives, synthetic procedures, structural, spectroscopic and analytical aspects, metal complexes, agrochemicals, neuroactive compounds and biomedical applications and transition-state analogue enzyme inhibitors, with particular emphasis on inhibitors of HIV protease, thrombin and human collagenase. Aminophosphonic and Aminophosphinic Acids is a valuable source of information for researchers working with these types of compounds in biomedical and agrochemical industries and all others working with synthetic analogues of biologically important molecules.
Aminophosphonic and Aminophosphinic Acids: Chemistry and Biological Activity,Valery P. Kukhar,Harry R. Hudson,John Wiley & Sons,0471891495,Aliphatic Chemistry,Amino acids,Analytical Biochemistry,Chemistry - Inorganic,Chemistry - Organic,Derivatives,Life Sciences - Biochemistry,Organophosphorus compounds,Phosphonic acids,Science,Science/Mathematics,Industrial applications of scientific research & technological innovation,Inorganic chemistry,Polymer chemistry,Science / Chemistry / Inorganic
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