Signalling Pathways in Apoptosis (Modern Genetics)
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Book Description
Apoptosis, or programmed cell death, is a necessary process by which a cell may die without adversely affecting its environment. It plays a crucial role in normal development, and in the body's defence mechanisms against disease. Too much cell death is destructive, leading to neurodegenerative diseases and impaired development. Conversely, too little cell death can lead to an increased susceptibility to cancer and sustained viral infection. Apoptosis is a matter of balance-a balance which is sustained or offset by various signaling pathways within the cell.
Dramatic progress has been made in the study of apoptosis over the past decade. One of the most rapidly expanding knowledge bases being established is on the molecular mechanisms controlled by a variety of gene products including Bcl-2, caspases, death receptors, and proteolytic targets, as well as the central role of the mitochondrion. The major challenge in apoptosis research is how the protein products involved operate in an intricate web o
Signalling Pathways in Apoptosis (Modern Genetics),Diane Watters,Martin Lavin,CRC,905702392X,Apoptosis,Cellular signal transduction,Cytology,Enzymology,Life Sciences - Anatomy & Physiology,Life Sciences - Biochemistry,Life Sciences - Cytology,Medical,Science,Signal Transduction,physiology,Cellular biology,Molecular biology,Science / Cytology
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